The chitinase PfCHT1 from the human malaria parasite Plasmodium falciparum lacks proenzyme and chitin-binding domains and displays unique substrate preferences

Within hours after the ingestion of a blood meal, the mosquito midgut epithelium synthesizes a chitinous sac, the peritrophic matrix. Plasmodium ookinetes traverse the peritrophic matrix while escaping the mosquito midgut. Chitinases (EC 3.2.1.14) are critical for parasite invasion of the midgut: th...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Proc Natl Acad Sci U S A
Päätekijät:	Vinetz, Joseph M., Dave, Sanat K., Specht, Charles A., Brameld, Kenneth A., Xu, Bo, Hayward, Rhian, Fidock, David A.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	National Academy of Sciences 1999
Aiheet:	Biological Sciences
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24190/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10570198/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.24.14061
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