Knockout of the Rodent Malaria Parasite Chitinase PbCHT1 Reduces Infectivity to Mosquitoes

During mosquito transmission, malaria ookinetes must cross a chitin-containing structure known as the peritrophic matrix (PM), which surrounds the infected blood meal in the mosquito midgut. In turn, ookinetes produce multiple chitinase activities presumably aimed at disrupting this physical barrier...

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Detalhes bibliográficos
Main Authors: Dessens, Johannes T., Mendoza, Jacqui, Claudianos, Charles, Vinetz, Joseph M., Khater, Emad, Hassard, Stuart, Ranawaka, Gaya R., Sinden, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98467/
https://ncbi.nlm.nih.gov/pubmed/11349074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.6.4041-4047.2001
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