Knockout of the Rodent Malaria Parasite Chitinase PbCHT1 Reduces Infectivity to Mosquitoes

During mosquito transmission, malaria ookinetes must cross a chitin-containing structure known as the peritrophic matrix (PM), which surrounds the infected blood meal in the mosquito midgut. In turn, ookinetes produce multiple chitinase activities presumably aimed at disrupting this physical barrier...

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Autori principali: Dessens, Johannes T., Mendoza, Jacqui, Claudianos, Charles, Vinetz, Joseph M., Khater, Emad, Hassard, Stuart, Ranawaka, Gaya R., Sinden, Robert E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Fungal and Parasitic Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC98467/
https://ncbi.nlm.nih.gov/pubmed/11349074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.6.4041-4047.2001
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