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Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion

Apoptotic and necrotic cell death are well characterized and are influenced by intracellular ATP levels. Poly(ADP-ribose) polymerase (PARP), a nuclear enzyme activated by DNA strand breaks, physiologically participates in DNA repair. Overactivation of PARP after cellular insults can lead to cell dea...

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Bibliografische gegevens
Hoofdauteurs: Ha, Hyo Chol, Snyder, Solomon H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1999
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC24176/
https://ncbi.nlm.nih.gov/pubmed/10570184
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