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Association of terminal deoxynucleotidyl transferase with Ku

Terminal deoxynucleotidyl transferase (TdT) catalyzes the addition of nucleotides at the junctions of rearranging Ig and T cell receptor gene segments, thereby generating antigen receptor diversity. Ku is a heterodimeric protein composed of 70- and 86-kDa subunits that binds DNA ends and is required...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Mahajan, Kiran N., Gangi-Peterson, Lisa, Sorscher, David H., Wang, Jingsong, Gathy, Karen N., Mahajan, Nupam P., Reeves, Westley H., Mitchell, Beverly S.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1999
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24167/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10570175/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.24.13926
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