Association of terminal deoxynucleotidyl transferase with Ku

Terminal deoxynucleotidyl transferase (TdT) catalyzes the addition of nucleotides at the junctions of rearranging Ig and T cell receptor gene segments, thereby generating antigen receptor diversity. Ku is a heterodimeric protein composed of 70- and 86-kDa subunits that binds DNA ends and is required...

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Auteurs principaux: Mahajan, Kiran N., Gangi-Peterson, Lisa, Sorscher, David H., Wang, Jingsong, Gathy, Karen N., Mahajan, Nupam P., Reeves, Westley H., Mitchell, Beverly S.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1999
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC24167/
https://ncbi.nlm.nih.gov/pubmed/10570175
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