Host Cells Participate in the In Vitro Effects of Novel Diamidine Analogues against Tachyzoites of the Intracellular Apicomplexan Parasites Neospora caninum and Toxoplasma gondii

The in vitro effects of 19 dicationic diamidine derivatives against the proliferative tachyzoite stages of the apicomplexan parasites Neospora caninum and Toxoplasma gondii were investigated. Four compounds (DB811, DB786, DB750, and DB766) with similar structural properties exhibited profound inhibi...

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Main Authors: Leepin, Angela, Stüdli, Angela, Brun, Reto, Stephens, Chad E., Boykin, David W., Hemphill, Andrew
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2008
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Mechanisms of Action: Physiological Effects
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2415759/
https://ncbi.nlm.nih.gov/pubmed/18362190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01236-07
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