Host Cells Participate in the In Vitro Effects of Novel Diamidine Analogues against Tachyzoites of the Intracellular Apicomplexan Parasites Neospora caninum and Toxoplasma gondii

The in vitro effects of 19 dicationic diamidine derivatives against the proliferative tachyzoite stages of the apicomplexan parasites Neospora caninum and Toxoplasma gondii were investigated. Four compounds (DB811, DB786, DB750, and DB766) with similar structural properties exhibited profound inhibi...

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Main Authors: Leepin, Angela, Stüdli, Angela, Brun, Reto, Stephens, Chad E., Boykin, David W., Hemphill, Andrew
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Mechanisms of Action: Physiological Effects
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2415759/
https://ncbi.nlm.nih.gov/pubmed/18362190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01236-07
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