Comparison of the Essential Cellular Functions of the Two murA Genes of Bacillus anthracis

Targeted antisense and gene replacement mutagenesis experiments demonstrate that only the murA1 gene and not the murA2 gene is required for the normal cellular growth of Bacillus anthracis. Antisense-based modulation of murA1 gene expression hypersensitizes cells to the MurA-specific antibiotic fosf...

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Detalhes bibliográficos
Main Authors: Kedar, G. C., Brown-Driver, Vickie, Reyes, Daniel R., Hilgers, Mark T., Stidham, Mark A., Shaw, Karen Joy, Finn, John, Haselbeck, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2415750/
https://ncbi.nlm.nih.gov/pubmed/18378720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01594-07
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