Fitness alteration of foot-and-mouth disease virus mutants: measurement of adaptability of viral quasispecies.
We document the rapid alteration of fitness of two foot-and-mouth disease virus (FMDV) mutants resistant to a neutralizing monoclonal antibody. Both mutants showed a selective disadvantage in BHK-21 cells when passaged in competition with their parental FMDV. Upon repeated replication of the mutants...
Gardado en:
| Publicado en: | J Virol |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
1991
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241436/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1645804/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.7.3954-3957.1991 |
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