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Biochemical and biological differences between E7 oncoproteins of the high- and low-risk human papillomavirus types are determined by amino-terminal sequences.

Differences in the biological characteristics of the high-risk human papillomavirus type 16 (HPV-16) and the low-risk HPV-6 E7 proteins were analyzed and shown to correlate with certain biochemical properties. To ascertain which region of E7 conferred these properties, chimeric E7 genes were constru...

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Bibliographic Details
Published in:J Virol
Main Authors: Münger, K, Yee, C L, Phelps, W C, Pietenpol, J A, Moses, H L, Howley, P M
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1991
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241434/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1645802/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.7.3943-3948.1991
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