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Protection against lethal cytomegalovirus infection by a recombinant vaccine containing a single nonameric T-cell epitope.
The regulatory immediate-early (IE) protein pp89 of murine cytomegalovirus induces CD8+ T lymphocytes that protect against lethal murine cytomegalovirus infection. The IE1 epitope is the only epitope of pp89 that is recognized by BALB/c cytolytic T lymphocytes (CTL). Using synthetic peptides, the op...
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| Published in: | J Virol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
1991
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241372/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1710286/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.7.3641-3646.1991 |
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