A poliovirus replicon containing the chloramphenicol acetyltransferase gene can be used to study the replication and encapsidation of poliovirus RNA.

A poliovirus replicon, FLC/REP, which incorporates the reporter gene chloramphenicol acetyltransferase (CAT) in place of the region encoding the capsid proteins VP4, VP2, and part of VP3 in the genome of poliovirus type 3, has been constructed. Transfection of cells indicates that the FLC/REP replic...

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Publié dans:	J Virol
Auteurs principaux:	Percy, N, Barclay, W S, Sullivan, M, Almond, J W
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1992
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241362/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1321286/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.8.5040-5046.1992
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