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Origin of INSL3-mediated testicular descent in therian mammals

Testicular descent is a unique physiological adaptation found in therian mammals allowing optimal spermatogenesis below core body temperature. Recent studies show that INSL3, produced by Leydig cells, and its receptor LGR8 (RXFP2) are essential for mediating the transabdominal phase of testicular de...

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Detalhes bibliográficos
Main Authors: Park, Jae-Il, Semyonov, Jenia, Chang, Chia Lin, Yi, Wei, Warren, Wesley, Hsu, Sheau Yu Teddy
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413165/
https://ncbi.nlm.nih.gov/pubmed/18463305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.7119108
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