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Activation of Calcitonin Receptor and Calcitonin Receptor-like Receptor by Membrane-anchored Ligands

G protein-coupled receptors (GPCRs) are the most important pharmaceutical targets, and more than 40% of drugs in use today modulate GPCR signaling. A major hurdle in the development of therapies targeting GPCRs is the drug candidate's nonselective actions in multiple tissues. The ability to spa...

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Autores principales: Chang, Chia Lin, Park, Jae-Il, Hsu, Sheau Yu Teddy
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2801234/
https://ncbi.nlm.nih.gov/pubmed/19903822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.020040
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