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Activation of Calcitonin Receptor and Calcitonin Receptor-like Receptor by Membrane-anchored Ligands
G protein-coupled receptors (GPCRs) are the most important pharmaceutical targets, and more than 40% of drugs in use today modulate GPCR signaling. A major hurdle in the development of therapies targeting GPCRs is the drug candidate's nonselective actions in multiple tissues. The ability to spa...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2801234/ https://ncbi.nlm.nih.gov/pubmed/19903822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.020040 |
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