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Myopic acts in the endocytic pathway to enhance signaling by the Drosophila EGF receptor

Summary Endocytosis of activated receptors can control signaling levels by exposing the receptors to novel downstream molecules or by leading to their degradation. Epidermal growth factor receptor (EGFR) signaling has critical roles in development and is misregulated in many cancers. We report here...

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Detalhes bibliográficos
Main Authors: Miura, Grant I., Roignant, Jean-Yves, Wassef, Michel, Treisman, Jessica E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413058/
https://ncbi.nlm.nih.gov/pubmed/18434417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.017202
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