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In vivo equilibrium of proinflammatory IL-17(+) and regulatory IL-10(+) Foxp3(+) RORγt(+) T cells
The nuclear hormone receptor retinoic acid receptor–related orphan receptor γt (RORγt) is required for the generation of T helper 17 cells expressing the proinflammatory cytokine interleukin (IL)-17. In vivo, however, less than half of RORγt(+) T cells express IL-17. We report here that RORγt(+) Tαβ...
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Päätekijät: | , , , , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
The Rockefeller University Press
2008
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2413035/ https://ncbi.nlm.nih.gov/pubmed/18504307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080034 |
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