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CCR5 Dictates the Equilibrium of Proinflammatory IL-17(+) and Regulatory Foxp3(+) T Cells in Fungal Infection
CCR5 is a chemotactic mediator for inflammatory cells as well as regulatory T cells (Tregs). In this study, we investigated the role of CCR5 during infection with the fungal pathogen Histoplasma capsulatum. Mice lacking CCR5 or treated with an mAb to CCL4 had impaired infiltration of inflammatory ce...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867240/ https://ncbi.nlm.nih.gov/pubmed/20335531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000032 |
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