Follicular dendritic cells control engulfment of apoptotic bodies by secreting Mfge8

The secreted phosphatidylserine-binding protein milk fat globule epidermal growth factor 8 (Mfge8) mediates engulfment of apoptotic germinal center B cells by tingible-body macrophages (TBMφs). Impairment of this process can contribute to autoimmunity. We show that Mfge8 is identical to the mouse fo...

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Detalhes bibliográficos
Main Authors: Kranich, Jan, Krautler, Nike Julia, Heinen, Ernst, Polymenidou, Magdalini, Bridel, Claire, Schildknecht, Anita, Huber, Christoph, Kosco-Vilbois, Marie H., Zinkernagel, Rolf, Miele, Gino, Aguzzi, Adriano
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Brief Definitive Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413028/
https://ncbi.nlm.nih.gov/pubmed/18490487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071019
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