Use of second-site homologous recombination to demonstrate that Epstein-Barr virus nuclear protein 3B is not important for lymphocyte infection or growth transformation in vitro.

Recombinant Epstein-Barr viruses with a stop codon inserted into the nuclear protein 3B (EBNA 3B) open reading frame were generated by second-site homologous recombination. These mutant viruses infected and growth transformed primary B lymphocytes, resulting in the establishment of lymphoblastoid ce...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Tomkinson, B, Kieff, E
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1992
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241048/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1313908/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.5.2893-2903.1992
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