A second origin of DNA plus-strand synthesis is required for optimal human immunodeficiency virus replication.

We recently reported that human immunodeficiency virus type 1 (HIV-1) unintegrated linear DNA displays a discontinuity in its plus strand, precisely defined by a second copy of the polypurine tract (PPT) located near the middle of the genome (P. Charneau and F. Clavel, J. Virol. 65:2415-2421, 1991)....

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Pubblicato in:	J Virol
Autori principali:	Charneau, P, Alizon, M, Clavel, F
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241038/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1560526/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.5.2814-2820.1992
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