Transformation of a continuous rat embryo fibroblast cell line requires three separate domains of simian virus 40 large T antigen.

Mouse C3H 10T1/2 cells and the established rat embryo fibroblast cell line REF-52 are two cell lines widely used in studies of viral transformation. Studies have shown that transformation of 10T1/2 cells requires only the amino-terminal 121 amino acids of simian virus 40 (SV40) large T antigen, whil...

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Pubblicato in:	J Virol
Autori principali:	Zhu, J, Rice, P W, Gorsch, L, Abate, M, Cole, C N
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241034/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1313902/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.5.2780-2791.1992
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