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Axis-dependent anisotropy in protein unfolding from integrated nonequilibrium single-molecule experiments, analysis, and simulation

We present a comprehensive study that integrates experimental and theoretical nonequilibrium techniques to map energy landscapes along well defined pull-axis specific coordinates to elucidate mechanisms of protein unfolding. Single-molecule force-extension experiments along two different axes of pho...

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Autors principals: Nome, Rene A., Zhao, Jason Ming, Hoff, Wouter D., Scherer, Norbert F.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2410074/
https://ncbi.nlm.nih.gov/pubmed/18093935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701281105
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