Phase I clinical trial and pharmacokinetic evaluation of NK911, a micelle-encapsulated doxorubicin

NK911 is a novel supramolecular nanocarrier designed for the enhanced delivery of doxorubicin (DXR) and is one of the successful polymer micelle systems to exhibit an efficient accumulation in solid tumours in mice. The purpose of this study was to define the maximum-tolerated dose (MTD) and dose-li...

詳細記述

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書誌詳細
主要な著者: Matsumura, Y, Hamaguchi, T, Ura, T, Muro, K, Yamada, Y, Shimada, Y, Shirao, K, Okusaka, T, Ueno, H, Ikeda, M, Watanabe, N
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2004
主題:
Clinical
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2410050/
https://ncbi.nlm.nih.gov/pubmed/15477860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602204
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