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Genetic diversity and purifying selection in West Nile virus populations are maintained during host switching

To investigate differential evolutionary rates and selective forces of WNV in hosts and vectors, we measured the genetic diversity that arose during alternating passage in mosquitoes and birds. Within-host genetic diversity was monitored in each of three experimentally passed replicates, and the com...

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Main Authors: Jerzak, Greta V. S., Brown, Ivy, Shi, Pei-Yong, Kramer, Laura D., Ebel, Gregory D.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409985/
https://ncbi.nlm.nih.gov/pubmed/18395240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.02.032
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