Khat (Catha edulis)-induced apoptosis is inhibited by antagonists of caspase-1 and -8 in human leukaemia cells

Khat chewing is a widespread habit that has a deep-rooted sociocultural tradition in Africa and the Middle East. The biological effects of khat are inadequately investigated and controversial. For the first time, we show that an organic extract of khat induces a selective type of cell death having a...

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Hlavní autoři: Dimba, E A O, Gjertsen, B T, Bredholt, T, Fossan, K O, Costea, D E, Francis, G W, Johannessen, A C, Vintermyr, O K
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2004
Témata:
Molecular and Cellular Pathology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409956/
https://ncbi.nlm.nih.gov/pubmed/15477863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602197
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