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Antibodies to CD20 and MHC class II antigen bound to B-lymphoma cells accumulate in shed cytoplasmic fragments

Antibodies (Abs) to CD20 and MHC class II antigen were found to exhibit a novel processing pathway after binding to the surface of RL B-lymphoma cells. The Abs were ‘excreted’ as a part of large cytoplasmic fragments. These fragments formed at cell–cell junctions, but gentle dispersal of the cells,...

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Detalhes bibliográficos
Main Authors: Michel, R B, Mattes, M J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409918/
https://ncbi.nlm.nih.gov/pubmed/15452546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602131
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