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ATGs help MHC class II, but inhibit MHC class I antigen presentation
We have recently shown that the LC3/Atg8 lipidation machinery of macroautophagy is involved in the internalization of MHC class I molecules. Decreased internalization in the absence of ATG5 or ATG7 leads to MHC class I surface stabilization on dendritic cells and macrophages, resulting in elevated C...
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| Publicado no: | Autophagy |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5082774/ https://ncbi.nlm.nih.gov/pubmed/27439741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1203488 |
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