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Pharmacokinetics of the nonsteroidal steroid sulphatase inhibitor 667 COUMATE and its sequestration into red blood cells in rats

Breast cancer is a major cause of mortality in Western countries and there is an urgent requirement for novel treatment strategies. The nonsteroidal sulphatase inhibitor 667 COUMATE inhibits hepatic steroid sulphatase and growth of oestrone sulphate stimulated tumours in the nitrosomethylurea-induce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ireson, C R, Chander, S K, Purohit, A, Parish, D C, Woo, L W L, Potter, B V L, Reed, M J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409900/
https://ncbi.nlm.nih.gov/pubmed/15328524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602130
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