Pharmacokinetics of the nonsteroidal steroid sulphatase inhibitor 667 COUMATE and its sequestration into red blood cells in rats

Breast cancer is a major cause of mortality in Western countries and there is an urgent requirement for novel treatment strategies. The nonsteroidal sulphatase inhibitor 667 COUMATE inhibits hepatic steroid sulphatase and growth of oestrone sulphate stimulated tumours in the nitrosomethylurea-induce...

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Detalhes bibliográficos
Main Authors: Ireson, C R, Chander, S K, Purohit, A, Parish, D C, Woo, L W L, Potter, B V L, Reed, M J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409900/
https://ncbi.nlm.nih.gov/pubmed/15328524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602130
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