Antitumour efficacy of VEGFR2 tyrosine kinase inhibitor correlates with expression of VEGF and its receptor VEGFR2 in tumour models

During the development of indazolylpyrimidines as novel and potent inhibitors of vascular endothelial growth factor (VEGF) receptor-2 (VEGFR2) tyrosine kinase, we observed that some human tumour xenografts are more sensitive to VEGFR2 kinase inhibitors than others. A better understanding of the basi...

詳細記述

保存先:
書誌詳細
主要な著者: Dev, I K, Dornsife, R E, Hopper, T M, Onori, J A, Miller, C G, Harrington, L E, Dold, K M, Mullin, R J, Johnson, J H, Crosby, R M, Truesdale, A T, Epperly, A H, Hinkle, K W, Cheung, M, Stafford, J A, Luttrell, D K, Kumar, R
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2004
主題:
Experimental Therapeutics
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409895/
https://ncbi.nlm.nih.gov/pubmed/15328520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602109
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料