Antitumour efficacy of VEGFR2 tyrosine kinase inhibitor correlates with expression of VEGF and its receptor VEGFR2 in tumour models

During the development of indazolylpyrimidines as novel and potent inhibitors of vascular endothelial growth factor (VEGF) receptor-2 (VEGFR2) tyrosine kinase, we observed that some human tumour xenografts are more sensitive to VEGFR2 kinase inhibitors than others. A better understanding of the basi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Dev, I K, Dornsife, R E, Hopper, T M, Onori, J A, Miller, C G, Harrington, L E, Dold, K M, Mullin, R J, Johnson, J H, Crosby, R M, Truesdale, A T, Epperly, A H, Hinkle, K W, Cheung, M, Stafford, J A, Luttrell, D K, Kumar, R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409895/
https://ncbi.nlm.nih.gov/pubmed/15328520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602109
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados