Analysis of epidermal growth factor receptor expression as a predictive factor for response to gefitinib (‘Iressa’, ZD1839) in non-small-cell lung cancer

Gefitinib (‘Iressa’, ZD1839) is an orally active epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor that has demonstrated antitumour activity and favourable tolerability in Phase II studies. We investigated whether EGFR expression levels could predict for response to gefitinib in pati...

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Bibliografiske detaljer
Main Authors: Parra, H S, Cavina, R, Latteri, F, Zucali, P A, Campagnoli, E, Morenghi, E, Grimaldi, G C, Roncalli, M, Santoro, A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2004
Fag:
Clinical
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409824/
https://ncbi.nlm.nih.gov/pubmed/15187994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601923
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