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Gefitinib (‘Iressa’, ZD1839) inhibits the growth response of bladder tumour cell lines to epidermal growth factor and induces TIMP2

The effect of EGF stimulation and its inhibition with gefitinib (‘Iressa’, ZD1839), an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, has been investigated in two EGFR-positive human bladder tumour cell lines, RT112 and RT4. The growth of RT112 cells in a medium containing 10% fo...

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Detalhes bibliográficos
Main Authors: Nutt, J E, Lazarowicz, H P, Mellon, J K, Lunec, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409696/
https://ncbi.nlm.nih.gov/pubmed/15083203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601768
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