A novel biweekly multidrug regimen of gemcitabine, oxaliplatin, 5-fluorouracil (5-FU), and folinic acid (FA) in pretreated patients with advanced colorectal carcinoma

Previous results suggest that GEM affects 5-fluorouracil (5-FU) metabolism and pharmacokinetics in cancer patients, while combined with oxaliplatin, levo-folinic acid, and 5-FU (GOLF regimen), at doses achievable in cancer patients, determines high cytotoxic and proapoptotic antitumour activity in c...

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Main Authors: Correale, P, Messinese, S, Caraglia, M, Marsili, S, Piccolomini, A, Petrioli, R, Ceciarini, F, Micheli, L, Nencini, C, Neri, A, Vuolo, G, Guarnieri, A, Abbruzzese, A, Prete, S D, Giorgi, G, Francini, G
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2004
Teme:
Clinical
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409742/
https://ncbi.nlm.nih.gov/pubmed/15150625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601783
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