Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer

We performed a multicentre randomised trial to compare the efficacy and toxicity of 12 weeks of 5-fluorouracil (5-FU) delivered by protracted intravenous infusion (PVI 5-FU) against the standard bolus regimen of 5-FU and folinic acid (5-FU/FA) given for 6 months as adjuvant treatment in colorectal c...

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Detalhes bibliográficos
Main Authors: Saini, A, Norman, A R, Cunningham, D, Chau, I, Hill, M, Tait, D, Hickish, T, Iveson, T, Lofts, F, Jodrell, D, Ross, P J, Oates, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2003
Assuntos:
Clinical
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741111/
https://ncbi.nlm.nih.gov/pubmed/12799627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600995
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