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Porphyrin synthesis from ALA derivatives for photodynamic therapy. In vitro and in vivo studies
The aim of this work was to test in vitro and in vivo the efficacy of the derivatives of 5-aminolevulinic acid (ALA): hexyl-ALA (He-ALA), undecanoyl-ALA and R,S-2-(hydroximethyl)tetrahydropyranyl-ALA (THP-ALA) as pro-photosensitising agents. The compounds were assayed in a cell line derived from a m...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2409714/ https://ncbi.nlm.nih.gov/pubmed/15083200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601722 |
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