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Porphyrin synthesis from ALA derivatives for photodynamic therapy. In vitro and in vivo studies

The aim of this work was to test in vitro and in vivo the efficacy of the derivatives of 5-aminolevulinic acid (ALA): hexyl-ALA (He-ALA), undecanoyl-ALA and R,S-2-(hydroximethyl)tetrahydropyranyl-ALA (THP-ALA) as pro-photosensitising agents. The compounds were assayed in a cell line derived from a m...

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Autori principali: Perotti, C, Fukuda, H, DiVenosa, G, MacRobert, A J, Batlle, A, Casas, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409714/
https://ncbi.nlm.nih.gov/pubmed/15083200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601722
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