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Induction of tumour blood flow stasis and necrosis: a new function for epinephrine similar to that of combretastatin A-4 derivative AVE8062 (AC7700)

AVE8062, a derivative of combretastatin A-4, has a strong stanching effect on tumour blood flow (TBF), which leads to complete blockage of nutrient supply to solid tumours and their necrosis. Previously, we reported that TBF stasis is due to increased arteriolar resistance caused by AVE8062 and a la...

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Autores principales: Hori, K, Saito, S
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409553/
https://ncbi.nlm.nih.gov/pubmed/14735207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601582
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