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Mitoxantrone resistance in a small cell lung cancer cell line is associated with ABCA2 upregulation

The aim of this study was to find factors that could explain the accumulation difference of mitoxantrone in the BCRP1-negative GLC4-MITO cell line compared to GLC4. Comparative genomic hybridisation (CGH) was applied to determine chromosomal differences between GLC4 and GLC4-MITO. Comparative genomi...

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Detalhes bibliográficos
Main Authors: Boonstra, R, Timmer-Bosscha, H, van Echten-Arends, J, van der Kolk, D M, van den Berg, A, de Jong, B, Tew, K D, Poppema, S, de Vries, E G E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409533/
https://ncbi.nlm.nih.gov/pubmed/15150577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601863
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