Cytotoxicity of rhein, the active metabolite of sennoside laxatives, is reduced by multidrug resistance-associated protein 1

Anthranoid laxatives, belonging to the anthraquinones as do anthracyclines, possibly increase colorectal cancer risk. Anthracyclines interfere with topoisomerase II, intercalate DNA and are substrates for P-glycoprotein and multidrug resistance-associated protein 1. P-glycoprotein and multidrug resi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: van Gorkom, B A P, Timmer-Bosscha, H, de Jong, S, van der Kolk, D M, Kleibeuker, J H, de Vries, E G E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2002
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375364/
https://ncbi.nlm.nih.gov/pubmed/11986786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600255
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados