Use of suppressor analysis to identify DNA polymerase mutations in herpes simplex virus which affect deoxynucleoside triphosphate substrate specificity.
Herpes simplex virus DNA polymerase mutations which map in the N-terminal part of the protein and appear to alter deoxynucleoside triphosphate (dNTP) substrate specificity are described. These mutations suppress a drug hypersensitivity associated with the downstream mutation, Aphr10. We suggest that...
Enregistré dans:
| Publié dans: | J Virol |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
1992
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240950/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1310785/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.3.1814-1816.1992 |
| Tags: |
Pas de tags, Soyez le premier à ajouter un tag!
|