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Local IGFBP-3 mRNA expression, apoptosis and risk of colorectal adenomas
BACKGROUND: IGF binding protein-3 (IGFBP-3) regulates the bioavailability of insulin-like growth factors I and II, and has both anti-proliferative and pro-apoptotic properties. Elevated plasma IGFBP-3 has been associated with reduced risk of colorectal cancer (CRC), but the role of tissue IGFBP-3 is...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2409350/ https://ncbi.nlm.nih.gov/pubmed/18498652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-143 |
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