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Simian virus 40 large T antigen stably complexes with a 185-kilodalton host protein.

Stable interactions between simian virus 40 large T antigen and host proteins are believed to play a major role in the ability of the viral protein to transform cells in culture and induce tumors in vivo. Two of these host proteins, the retinoblastoma susceptibility protein (pRB) and p53, are produc...

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Detalles Bibliográficos
Main Authors: Kohrman, D C, Imperiale, M J
Formato: Artigo
Idioma:Inglês
Publicado: 1992
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC240927/
https://ncbi.nlm.nih.gov/pubmed/1310776
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