Lipoteichoic acid may affect the pathogenesis of PBC-like bile duct damage and might be involved in systemic multifocal epithelial inflammations in chronic colitis-harboring TCRα(−/−) × AIM(−/−) mice

BACKGROUND: Chronic colitis-harboring TCRα(−/−) × AIM(−/−) mice showed PBC-like bile duct damage in the liver. Bacterial infection is one of the candidates for the pathogenesis of PBC. We demonstrated that the bacterial cell wall component lipotheicoic acid (LTA)was detected at sites of inflammation...

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Main Authors: Haruta, Ikuko, Hashimoto, Etsuko, Shibata, Noriyuki, Kato, Yoichiro, Kobayashi, Makio, Shiratori, Keiko
Format: Artigo
Language:Inglês
Published: Informa Healthcare 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409170/
https://ncbi.nlm.nih.gov/pubmed/17612899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/08916930701402392
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