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The adenovirus E3 14.5-kilodalton protein, which is required for down-regulation of the epidermal growth factor receptor and prevention of tumor necrosis factor cytolysis, is an integral membrane protein oriented with its C terminus in the cytoplasm.

We previously reported that the adenovirus type 5 E3 14.5-kilodalton protein (14.5K) forms a complex with E3 10.4K and that both proteins are required to down-regulate the epidermal growth factor receptor in adenovirus-infected human cells. Both proteins are also required to prevent cytolysis by tum...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Krajcsi, P, Tollefson, A E, Anderson, C W, Wold, W S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240906/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1531370/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.3.1665-1673.1992
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