The adenovirus E3-14.7K protein and the E3-10.4K/14.5K complex of proteins, which independently inhibit tumor necrosis factor (TNF)-induced apoptosis, also independently inhibit TNF-induced release of arachidonic acid.

Tumor necrosis factor (TNF) is an inflammatory cytokine that inhibits the replication of many viruses in cultured cells. We have reported that adenovirus (Ad) infection of TNF-resistant mouse cells renders them susceptible to lysis by TNF and that two sets of proteins encoded by the E3 transcription...

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Detalhes bibliográficos
Main Authors: Krajcsi, P, Dimitrov, T, Hermiston, T W, Tollefson, A E, Ranheim, T S, Vande Pol, S B, Stephenson, A H, Wold, W S
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC190440/
https://ncbi.nlm.nih.gov/pubmed/8763993
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