Prevalence of bortezomib-resistant constitutive NF-kappaB activity in mantle cell lymphoma

BACKGROUND: The proteasome inhibitor bortezomib can inhibit activation of the transcription factor NF-κB, a mechanism implicated in its anti-neoplastic effects observed in mantle cell lymphoma (MCL). However, NF-κB can be activated through many distinct mechanisms, including proteasome independent p...

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Bibliografiske detaljer
Main Authors: Yang, David T, Young, Ken H, Kahl, Brad S, Markovina, Stephanie, Miyamoto, Shigeki
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408930/
https://ncbi.nlm.nih.gov/pubmed/18489772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-7-40
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