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The Chorionic Enhancer Is Dispensable for Regulated Expression of the Human Renin Gene

We tested the hypothesis that a transcriptional enhancer (CE), previously identified to increase human renin expression in choriodecidual cells is required to mediate tissue-specific, cell-specific and regulated expression of human renin in transgenic mice. Recombineering was used to delete the CE u...

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Bibliographic Details
Main Authors: Zhou, Xiyou, Sigmund, Curt D.
Format: Artigo
Language:Inglês
Published: 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408876/
https://ncbi.nlm.nih.gov/pubmed/18077515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00780.2007
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