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Requirement for enhancer specificity in immunoglobulin heavy chain locus regulation

The intronic Eμ enhancer has been implicated in immunoglobulin heavy chain (IgH) locus transcription, VDJ recombination, class switch recombination (CSR) and somatic hypermutation (SHM). How Eμ controls these diverse mechanisms is still largely unclear, but transcriptional enhancer activity is thoug...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kuzin, Igor I., Bagaeva, Ludmila, Young, Faith M., Bottaro, Andrea
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408828/
https://ncbi.nlm.nih.gov/pubmed/18490744
Tagiau: Ychwanegu Tag
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