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Requirement for enhancer specificity in immunoglobulin heavy chain locus regulation

The intronic Eμ enhancer has been implicated in immunoglobulin heavy chain (IgH) locus transcription, VDJ recombination, class switch recombination (CSR) and somatic hypermutation (SHM). How Eμ controls these diverse mechanisms is still largely unclear, but transcriptional enhancer activity is thoug...

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Bibliografische gegevens
Hoofdauteurs: Kuzin, Igor I., Bagaeva, Ludmila, Young, Faith M., Bottaro, Andrea
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408828/
https://ncbi.nlm.nih.gov/pubmed/18490744
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